細胞工学
主な業績
2025
Toyoda Y, Masuda F, Saitoh S.
Phosphorylation of the Aly3 C-terminus impedes aberrant endocytosis of Schizosaccharomyces pombe hexose transporter Ght5.
J Cell Sci. 2025 Mar 31: jcs.263572.
Suma M, Arakawa O, Tahara Y, Sajiki K, Saitoh S, Yanagida M.
In quiescent G0 phase, Schizosaccharomyces pombe Mis4 ensures full nuclear separation during the subsequent M phase.
J Cell Sci. 2025 Mar 1;138(5): jcs.263747.
Ishikawa K, Soejima S, Nishimura T, Saitoh S.
Arrayed CRISPRi library to suppress genes required for Schizosaccharomyces pombe viability.
J Cell Biol. 2025 Jan 6;224(1): e202404085.
2024
Ishikawa K, Saitoh S.
Proliferation Analyses of Conditional Knockdown Strains Using CRISPR Interference in Fission Yeast.
Methods Mol Biol. 2024 Nov 12; 2862:171-186.
2023
Mori A, Uehara L, Toyoda Y, Masuda F, Soejima S, Saitoh S, Yanagida M.
In fission yeast, 65 non-essential mitochondrial proteins related to respiration and stress become essential in low-glucose conditions.
R Soc Open Sci. 2023 Oct 18;10(10):230404.
Ishikawa K, Soejima S, Saitoh S.
Genetic knockdown of genes that are obscure, conserved and essential using CRISPR interference methods in the fission yeast S. pombe.
J Cell Sci. 2023 May 1;136(9): jcs261186.
Ishikawa K, Saitoh S.
Transcriptional Regulation Technology for Gene Perturbation in Fission Yeast.
Biomolecules. 2023 Apr 21;13(4):716.
2022
Morimoto Y, Saitoh S, Takayama Y.
Growth conditions inducing G1 cell cycle arrest enhance lipid production in the oleaginous yeast Lipomyces starkeyi.
J Cell Sci. 2022 Aug 15; 135(16): jcs259996.
Maruyama T, Hayashi K, Matsui K, Maekawa Y, Shimasaki T, Ohtsuka H, Saitoh S, Aiba H.
Characterization of hexose transporter genes in the views of the chronological life span and glucose uptake in fission yeast.
J Gen Appl Microbiol. 2022 July 2; jgam.2022.05.006.
豊田雄介
グルコース飢餓への適応における TORC2 経路の役割－アミノ酸が糖代謝を制御するしくみ
実験医学. 2022 May 1; 40(7); 1124-1130.
2021
Toyoda Y, Saitoh S
Fission Yeast TORC2 Signaling Pathway Ensures Cell Proliferation under Glucose-Limited, Nitrogen-Replete Conditions
Biomolecules 2021, 11(10), 1465: biom11101465
Uehara L, Saitoh S, Mori A, Sajiki K, Toyoda Y, Masuda F, Soejima S, Tahara Y, Yanagida Y
Multiple nutritional phenotypes of fission yeast mutants defective in genes encoding essential mitochondrial proteins
Open Biol (2021) 11 (4): rsob.200369
Toyoda Y, Soejima S, Masuda F, Saitoh S
TORC2 inhibition of α-arrestin Aly3 mediates cell surface persistence of S. pombe Ght5 glucose transporter in low glucose
J Cell Sci (2021) 134 (10): jcs257485.
Ishikawa K, Soejima S, Masuda F, Saitoh S
Implementation of dCas9-mediated CRISPRi in the fission yeast Schizosaccharomyces pombe
G3 Genes|Genomes|Genetics, Volume 11, Issue 4, April 2021, jkab051. 同誌のFeatured Articleに選ばれました。
2019
Takeda A, Saitoh S, Ohkura H, Sawin KE, Goshima G
Identification of 15 New Bypassable Essential Genes of Fission Yeast
Cell Struct Funcｔ, 2019 Sep 27;44(2):113-119.
2018
Toyoda Y, Akarlar B, Sarov M, Ozlu N, Saitoh S
Extracellular glucose level regulates dependence on GRP78 for cell surface localization of multipass transmembrane proteins in HeLa cells
FEBS Letter, 2018 Oct;592(19):3295-3304.
Nakazawa N, Teruya T,Sajiki K, Kumada K,Villar-Briones A, Arakawa O, Takada J, Saitoh S, Yanagida M
The putative ceramide-conjugation protein Cwh43 regulates G0 quiescence, nutrient metabolism and lipid homeostasis in fission yeast
J Cell Sci 2018 131: jcs217331 doi: 10.1242/jcs.217331, 21 August 2018
2016
Masuda F, Ishii M, Mori A, Uehara L, Yanagida M, Takeda K, Saitoh S.
Glucose restriction induces transient G2 cell cycle arrest extending cellular chronological lifespan.
Sci. Rep. 2016 Jan 25;6:19629
doi: 10.1038
2015
Saitoh S, Mori A, Uehara L, Masuda F, Soejima S, Yanagida M.
Mechanisms of expression and translocation of major fission yeast glucose transporters regulated by CaMKK/phosphatases, nuclear shuttling, and TOR.
Mol. Biol. Cell 2015 Jan 15;26(2):373-86
PMID:25411338
Toyoda Y, Saitoh S.
Adaptive regulation of glucose transport, glycolysis and respiration for cell proliferation.
BioMol. Concepts 2015 Dec;6(5-6):423-30
PMID:26418646
2014
Saitoh S, Yanagida M.
Does a shift to limited glucose activate checkpoint control in fission yeast?
FEBS Lett. 2014 Aug 1;588(15):2373-8.
PMID:24815688
ARCHIVE
- 齋藤成昭
- 豊田雄介
- 寺田祐子